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RDSP: A Complex Pathway to Long-Term Security

  The Registered Disability Savings Plan (RDSP) is often described as one of Canada’s most powerful yet underutilized financial tools. Designed to help people with disabilities and their families save for the future, the RDSP comes with unique benefits that make its administrative hurdles worthwhile. At its core, the RDSP offers two major advantages: Government Grants and Bonds : Eligible contributions can be matched by the federal government through generous grants, and low-income beneficiaries may also qualify for bonds—even without personal contributions. Tax-Deferred Growth : Investments inside the RDSP grow tax-free until funds are withdrawn, allowing savings to compound over time. The paperwork, eligibility rules, and withdrawal restrictions can feel daunting. Families often face challenges navigating the application process, understanding contribution limits, and planning around complex withdrawal rules. Yet, for those who persist, the payoff is significant: thousands...
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Alzheimer’s Drug Donanemab Receives FDA Advisers’ Endorsement for Slowing Disease Progression

 

A significant milestone has been reached in the fight against Alzheimer’s disease. Eli Lilly’s closely watched Alzheimer’s drug, donanemab, has won the unanimous backing of federal health advisers. The drug is specifically intended for people with mild dementia caused by this brain-robbing disease.

The decision by the Food and Drug Administration (FDA) advisers comes after careful consideration of the drug’s benefits and risks. Donanemab has demonstrated the ability to modestly slow cognitive decline and memory problems associated with Alzheimer’s. Although it’s not a cure, this endorsement represents a promising step forward in managing the disease.

Here are the key points:

  1. Effectiveness: Donanemab has shown effectiveness in slowing cognitive decline. Patients who received monthly intravenous infusions of the drug declined about 35% more slowly than those who received a placebo.
  2. Risk Assessment: The FDA panel weighed the risks, including side effects like brain swelling and bleeding, which will need monitoring. Despite these risks, the panel concluded that the drug’s benefits outweighed them.
  3. Tau Protein Screening: Unlike previous concerns about tau protein screening, most panelists believed there was enough evidence to prescribe the drug broadly without requiring such screening.
  4. FDA Decision: The FDA will make the final decision on approval later this year. If approved, donanemab would become only the second Alzheimer’s drug in the U.S. shown to convincingly slow cognitive decline.

This endorsement brings hope to individuals and families affected by Alzheimer’s, and we eagerly await the FDA’s final decision. Stay tuned for further updates on this groundbreaking development! 

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